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Category: Carbon core metabolism
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2. Metabolism
2.2. Carbon metabolism
2.2.1. Carbon core metabolism
2.2.1.1. Glycolysis
Name | Function |
cggR | transcriptional regulator |
eno | enzyme in glycolysis/ gluconeogenesis |
fbaA | enzyme in glycolysis/ gluconeogenesis |
gapA | catabolic enzyme in glycolysis |
glcT | control of glucose uptake |
mgsA | bypass of glycolysis |
pfkA | catabolic enzyme in glycolysis |
pgi | enzyme in glycolysis / gluconeogenesis |
pgk | enzyme in glycolysis/ gluconeogenesis |
pgm | enzyme in glycolysis / gluconeogenesis |
ptsG | glucose transport and phosphorylation, control of [protein|BC0DF593AE969F1DBC5E9E2BACF1C00BE4FEE449|GlcT] activity |
pyk | catabolic enzyme in glycolysis |
tpi | enzyme in glycolysis/ gluconeogenesis |
2.2.1.2. Gluconeogenesis
Name | Function |
ccpN | repressor of genes involved in gluconeogenesis ([gene|C1B89BD3DD27CD566018558D3A7845FB451056F0|gapB], [gene|74D4616D1A550D87182FAAC2A4AF6E04F81E1572|pckA]) and of [gene|FC93BA60BD185DE5EF31D5605F0B8294EC2E8E5A|sr1] |
eno | enzyme in glycolysis/ gluconeogenesis |
fbaA | enzyme in glycolysis/ gluconeogenesis |
fbp | gluconeogenesis |
gapB | anabolic enzyme in gluconeogenesis |
glpX | gluconeogenesis |
pckA | synthesis of phosphoenolpyruvate |
pgi | enzyme in glycolysis / gluconeogenesis |
pgk | enzyme in glycolysis/ gluconeogenesis |
pgm | enzyme in glycolysis / gluconeogenesis |
tpi | enzyme in glycolysis/ gluconeogenesis |
yqfL | inhibits [protein|2234D81F8F9B92EAF1CF6F73BEC92D4DE54E2636|CcpN] activity |
2.2.1.3. Pentose phosphate pathway
Name | Function |
gndA | pentose phosphate pathway |
rpe | pentose phosphate pathway |
tkt | pentose phosphate pathway |
ykgB | pentose phosphate pathway |
ywjH | pentose phosphate pathway |
ywlF | pentose phosphate pathway |
zwf | initiation of the pentose phosphate pathway |
2.2.1.4. TCA cycle
Name | Function |
ccpC | regulation of tricarboxylic acid branch of the TCA cycle |
citB | TCA cycle |
citG | TCA cycle |
citZ | TCA cycle |
icd | TCA cycle |
mdh | TCA cycle |
odhA | TCA cycle |
odhB | TCA cycle |
pdhA | links glycolysis and TCA cycle |
pdhB | links glycolysis and TCA cycle |
pdhC | links glycolysis and TCA cycle |
pdhD | links glycolysis and TCA cycle, enzyme in TCA cycle |
pycA | replenishment of the oxaloacetate pool |
sdhA | TCA cycle |
sdhB | TCA cycle |
sdhC | TCA cycle |
sucC | TCA cycle |
sucD | TCA cycle |
2.2.1.5. Overflow metabolism
Name | Function |
ackA | overflow metabolism |
alsD | overflow metabolism |
alsR | regulation of acetoin synthesis ([gene|AAA45830B9C5428CADFA5551D33B513E9B1B7C8E|alsS]-[gene|355E70F55A28C6C2C24E8E326EFB673AC303FBEE|alsD]) |
alsS | overflow metabolism |
bdhA | overflow metabolism, fermentation |
lctP | lactate excretion |
ldh | overflow metabolism, fermentation |
pta | overflow metabolism |
rex | regulation of fermentation and anaerobic respiration |
important original publications
20933603, 19193632 ,12850135,11489127,19917605,18586936,9131624 ,18302748,24727859 reviews
11018147,19202299,17982469,16102602,22545791